Cargando…
Mutational Studies of the Mersacidin Leader Reveal the Function of Its Unique Two-Step Leader Processing Mechanism
[Image: see text] The class II lanthipeptide mersacidin, a ribosomally synthesized and post-translationally modified peptide (RiPP), displays unique intramolecular structures, including a very small lanthionine ring. When applied in the growing field of RiPP engineering, these can add unique feature...
Autores principales: | Viel, Jakob H., Kuipers, Oscar P. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2022
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9127955/ https://www.ncbi.nlm.nih.gov/pubmed/35504017 http://dx.doi.org/10.1021/acssynbio.2c00088 |
Ejemplares similares
-
Heterologous Expression of Mersacidin in Escherichia
coli Elucidates the Mode of Leader Processing
por: Viel, Jakob H., et al.
Publicado: (2021) -
Characterization of Leader Processing Shows That Partially Processed Mersacidin Is Activated by AprE After Export
por: Viel, Jakob H., et al.
Publicado: (2021) -
Modular Use of
the Uniquely Small Ring A of Mersacidin
Generates the Smallest Ribosomally Produced Lanthipeptide
por: Viel, Jakob H., et al.
Publicado: (2022) -
Dissecting Structural and Functional Diversity of the Lantibiotic Mersacidin
por: Appleyard, Antony N., et al.
Publicado: (2009) -
Leader- and Terminal
Residue Requirements for Circularin
A Biosynthesis Probed by Systematic Mutational Analyses
por: Liu, Fangfang, et al.
Publicado: (2023)