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Mutational Studies of the Mersacidin Leader Reveal the Function of Its Unique Two-Step Leader Processing Mechanism

[Image: see text] The class II lanthipeptide mersacidin, a ribosomally synthesized and post-translationally modified peptide (RiPP), displays unique intramolecular structures, including a very small lanthionine ring. When applied in the growing field of RiPP engineering, these can add unique feature...

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Detalles Bibliográficos
Autores principales: Viel, Jakob H., Kuipers, Oscar P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9127955/
https://www.ncbi.nlm.nih.gov/pubmed/35504017
http://dx.doi.org/10.1021/acssynbio.2c00088

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