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The long noncoding RNA Malat1 regulates CD8(+) T cell differentiation by mediating epigenetic repression

During an immune response to microbial infection, CD8(+) T cells give rise to short-lived effector cells and memory cells that provide sustained protection. Although the transcriptional programs regulating CD8(+) T cell differentiation have been extensively characterized, the role of long noncoding...

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Detalles Bibliográficos
Autores principales: Kanbar, Jad N., Ma, Shengyun, Kim, Eleanor S., Kurd, Nadia S., Tsai, Matthew S., Tysl, Tiffani, Widjaja, Christella E., Limary, Abigail E., Yee, Brian, He, Zhaoren, Hao, Yajing, Fu, Xiang-Dong, Yeo, Gene W., Huang, Wendy J., Chang, John T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9127983/
https://www.ncbi.nlm.nih.gov/pubmed/35593887
http://dx.doi.org/10.1084/jem.20211756

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