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The Remarkable Selectivity of Nirmatrelvir
[Image: see text] The SARS-CoV-2 main protease is among the most attractive targets for the development of therapeutic interventions for COVID-19. Successful candidate agents will not only possess potent on-target activity versus SARS-CoV-2 M(pro) but also minimal polypharmacology versus human cyste...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9128007/ https://www.ncbi.nlm.nih.gov/pubmed/35702394 http://dx.doi.org/10.1021/acsptsci.2c00065 |