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HMGB1 mediates invasion and PD-L1 expression through RAGE-PI3K/AKT signaling pathway in MDA-MB-231 breast cancer cells

BACKGROUND: High-mobility group box 1 (HMGB1) is increased in breast cancer cells as the result of exposure to the secreted substances from cancer-associated fibroblasts and plays a crucial role in cancer progression and drug resistance. Its effect, however, on the expression of programmed death lig...

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Detalles Bibliográficos
Autores principales: Amornsupak, Kamolporn, Thongchot, Suyanee, Thinyakul, Chanida, Box, Carol, Hedayat, Somaieh, Thuwajit, Peti, Eccles, Suzanne A., Thuwajit, Chanitra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9128129/
https://www.ncbi.nlm.nih.gov/pubmed/35610613
http://dx.doi.org/10.1186/s12885-022-09675-1