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Single‐cell transcriptomics provides insights into the origin and microenvironment of human oesophageal high‐grade intraepithelial neoplasia

BACKGROUND: High‐grade intraepithelial neoplasia (HIN) is the precursor of oesophageal squamous cell carcinoma. The molecular and functional properties of HIN are determined by intrinsic origin cells and the extrinsic microenvironment. Yet, these factors are poorly understood. METHODS: We performed...

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Detalles Bibliográficos
Autores principales: Liao, Guobin, Dai, Nan, Xiong, Tiantian, Wang, Liang, Diao, Xinwei, Xu, Zhizhen, Ni, Yuanli, Chen, Dingrong, Jiang, Airui, Lin, Hui, Dai, Shuangshuang, Bai, Jianying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9128161/
https://www.ncbi.nlm.nih.gov/pubmed/35608199
http://dx.doi.org/10.1002/ctm2.874