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Histone H1.2 promotes hepatocarcinogenesis by regulating signal transducer and activator of transcription 3 signaling

Linker histone H1.2 (H1.2), encoded by HIST1H1C (H1C), is a major H1 variant in somatic cells. Among five histone H1 somatic variants, upregulated H1.2 was found in human hepatocellular carcinoma (HCC) samples and in a diethylnitrosamine (DEN)‐induced HCC mouse model. In vitro, H1.2 overexpression a...

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Detalles Bibliográficos
Autores principales:	Wang, Qing, Chen, Yuchen, Xie, Yunhao, Yang, Dong, Sun, Yuyan, Yuan, Yangmian, Chen, Hong, Zhang, Yu, Huang, Kun, Zheng, Ling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	ORIGINAL ARTICLES
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9128180/ https://www.ncbi.nlm.nih.gov/pubmed/35294987 http://dx.doi.org/10.1111/cas.15336

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