Cargando…

Novel antiangiogenic therapy targeting biglycan using tumor endothelial cell‐specific liposomal siRNA delivery system

Tumor blood vessels play important roles in tumor progression and metastasis. Targeting tumor endothelial cells (TECs) is one of the strategies for cancer therapy. We previously reported that biglycan, a small leucine‐rich proteoglycan, is highly expressed in TECs. TECs utilize biglycan in an autocr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Maishi, Nako, Sakurai, Yu, Hatakeyama, Hiroto, Umeyama, Yui, Nakamura, Takashi, Endo, Rikito, Alam, Mohammad Towfik, Li, Cong, Annan, Dorcas Akuba‐Muhyia, Kikuchi, Hiroshi, Morimoto, Hirofumi, Morimoto, Masahiro, Akiyama, Kosuke, Ohga, Noritaka, Hida, Yasuhiro, Harashima, Hideyoshi, Hida, Kyoko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9128192/ https://www.ncbi.nlm.nih.gov/pubmed/35266253 http://dx.doi.org/10.1111/cas.15323

Ejemplares similares

Tumor Endothelial Cell—A Biological Tool for Translational Cancer Research
por: Annan, Dorcas Akuba-Muhyia, et al.
Publicado: (2020)

Inhibition of stromal biglycan promotes normalization of the tumor microenvironment and enhances chemotherapeutic efficacy
por: Cong, Li, et al.
Publicado: (2021)

Tumour endothelial cells in high metastatic tumours promote metastasis via epigenetic dysregulation of biglycan
por: Maishi, Nako, et al.
Publicado: (2016)

Biglycan, tumor endothelial cell secreting proteoglycan, as possible biomarker for lung cancer
por: Morimoto, Hirofumi, et al.
Publicado: (2021)

Hypoxia-Induced Reactive Oxygen Species Cause Chromosomal Abnormalities in Endothelial Cells in the Tumor Microenvironment
por: Kondoh, Miyako, et al.
Publicado: (2013)

ROS enhance angiogenic properties via regulation of NRF2 in tumor endothelial cells
por: Hojo, Takayuki, et al.
Publicado: (2017)

Identification of novel targets for antiangiogenic therapy by comparing the gene expressions of tumor and normal endothelial cells
por: Otsubo, Tsuguteru, et al.
Publicado: (2014)

Contribution of Tumor Endothelial Cells in Cancer Progression
por: Hida, Kyoko, et al.
Publicado: (2018)

miR-1246 in tumor extracellular vesicles promotes metastasis via increased tumor cell adhesion and endothelial cell barrier destruction
por: Morimoto, Masahiro, et al.
Publicado: (2023)

Tumor Endothelial Heterogeneity in Cancer Progression
por: Maishi, Nako, et al.
Publicado: (2019)

Tumor endothelial cells with high aldehyde dehydrogenase activity show drug resistance
por: Hida, Kyoko, et al.
Publicado: (2017)

Biglycan is a specific marker and an autocrine angiogenic factor of tumour endothelial cells
por: Yamamoto, K, et al.
Publicado: (2012)

miRNA-1246 in extracellular vesicles secreted from metastatic tumor induces drug resistance in tumor endothelial cells
por: Torii, Chisaho, et al.
Publicado: (2021)

Carbonic anhydrase 2 (CAII) supports tumor blood endothelial cell survival under lactic acidosis in the tumor microenvironment
por: Annan, Dorcas A., et al.
Publicado: (2019)

Identification and expression of troponin T, a new marker on the surface of cultured tumor endothelial cells by aptamer ligand
por: Ara, Mst Naznin, et al.
Publicado: (2014)

Development of a Novel DNA Aptamer Ligand Targeting to Primary Cultured Tumor Endothelial Cells by a Cell-Based SELEX Method
por: Ara, Mst. Naznin, et al.
Publicado: (2012)

Suprabasin as a novel tumor endothelial cell marker
por: Alam, Mohammad T, et al.
Publicado: (2014)

Identification of Tumor Endothelial Cells with High Aldehyde Dehydrogenase Activity and a Highly Angiogenic Phenotype
por: Ohmura-Kakutani, Hitomi, et al.
Publicado: (2014)

Tumor-Derived Microvesicles Induce Proangiogenic Phenotype in Endothelial Cells via Endocytosis
por: Kawamoto, Taisuke, et al.
Publicado: (2012)

Tumor endothelial cells accelerate tumor metastasis
por: Maishi, Nako, et al.
Publicado: (2017)

Angiogenic inhibitor pre‐administration improves the therapeutic effects of immunotherapy
por: Sato, Mineyoshi, et al.
Publicado: (2023)

The silencing of indoleamine 2,3-dioxygenase 1 (IDO1) in dendritic cells by siRNA-loaded lipid nanoparticles enhances cell-based cancer immunotherapy
por: Endo, Rikito, et al.
Publicado: (2019)

Development of Immortalized Human Tumor Endothelial Cells from Renal Cancer
por: Maishi, Nako, et al.
Publicado: (2019)

Intracellular stability of 2′-OMe-4′-thioribonucleoside modified siRNA leads to long-term RNAi effect
por: Takahashi, Mayumi, et al.
Publicado: (2012)

HuR keeps an angiogenic switch on by stabilising mRNA of VEGF and COX-2 in tumour endothelium
por: Kurosu, T, et al.
Publicado: (2011)

Antiviral effect of cetylpyridinium chloride in mouthwash on SARS-CoV-2
por: Takeda, Ryo, et al.
Publicado: (2022)

Skeletal-Vascular Interactions in Bone Development, Homeostasis, and Pathological Destruction
por: Watanabe, Haruhisa, et al.
Publicado: (2023)

Lysyl oxidase secreted by tumour endothelial cells promotes angiogenesis and metastasis
por: Osawa, T, et al.
Publicado: (2013)

The oral bacterium Streptococcus mutans promotes tumor metastasis by inducing vascular inflammation
por: Yu, Li, et al.
Publicado: (2022)

In vivo therapeutic potential of Dicer-hunting siRNAs targeting infectious hepatitis C virus.
por: Watanabe, Tsunamasa, et al.
Publicado: (2014)

Investigation of siRNA Nanoparticle Formation Using Mono-Cationic Detergents and Its Use in Gene Silencing in Human HeLa Cells
por: Yamada, Yuma, et al.
Publicado: (2013)

Optimization of a siRNA Carrier Modified with a pH-Sensitive Cationic Lipid and a Cyclic RGD Peptide for Efficiently Targeting Tumor Endothelial Cells
por: Hada, Tomoya, et al.
Publicado: (2015)

Significant association of Yamamoto-Kohama classification and pathological depth of invasion with cervical lymph node metastasis in early-stage tongue squamous cell carcinoma (Stage I/II)
por: Kakuguchi, Wataru, et al.
Publicado: (2023)

Small-sized, stable lipid nanoparticle for the efficient delivery of siRNA to human immune cell lines
por: Nakamura, Takashi, et al.
Publicado: (2016)

STING agonist loaded lipid nanoparticles overcome anti-PD-1 resistance in melanoma lung metastasis via NK cell activation
por: Nakamura, Takashi, et al.
Publicado: (2021)

TNF‐α enhances TGF‐β‐induced endothelial‐to‐mesenchymal transition via TGF‐β signal augmentation
por: Yoshimatsu, Yasuhiro, et al.
Publicado: (2020)

Bovine Lactoferrin Suppresses Tumor Angiogenesis through NF-κB Pathway Inhibition by Binding to TRAF6
por: Ayuningtyas, Nurina Febriyanti, et al.
Publicado: (2023)

The Role of Decorin and Biglycan Signaling in Tumorigenesis
por: Diehl, Valentina, et al.
Publicado: (2021)

Biglycan regulates bone development and regeneration
por: Shainer, Reut, et al.
Publicado: (2023)

Breast cancer dataset with biomarker Biglycan
por: Silva Neto, Pedro Clarindo da, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_57b3mond0961pill1htkib10c3