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Novel antiangiogenic therapy targeting biglycan using tumor endothelial cell‐specific liposomal siRNA delivery system

Tumor blood vessels play important roles in tumor progression and metastasis. Targeting tumor endothelial cells (TECs) is one of the strategies for cancer therapy. We previously reported that biglycan, a small leucine‐rich proteoglycan, is highly expressed in TECs. TECs utilize biglycan in an autocr...

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Detalles Bibliográficos
Autores principales: Maishi, Nako, Sakurai, Yu, Hatakeyama, Hiroto, Umeyama, Yui, Nakamura, Takashi, Endo, Rikito, Alam, Mohammad Towfik, Li, Cong, Annan, Dorcas Akuba‐Muhyia, Kikuchi, Hiroshi, Morimoto, Hirofumi, Morimoto, Masahiro, Akiyama, Kosuke, Ohga, Noritaka, Hida, Yasuhiro, Harashima, Hideyoshi, Hida, Kyoko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9128192/
https://www.ncbi.nlm.nih.gov/pubmed/35266253
http://dx.doi.org/10.1111/cas.15323

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