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Novel antiangiogenic therapy targeting biglycan using tumor endothelial cell‐specific liposomal siRNA delivery system
Tumor blood vessels play important roles in tumor progression and metastasis. Targeting tumor endothelial cells (TECs) is one of the strategies for cancer therapy. We previously reported that biglycan, a small leucine‐rich proteoglycan, is highly expressed in TECs. TECs utilize biglycan in an autocr...
Autores principales: | Maishi, Nako, Sakurai, Yu, Hatakeyama, Hiroto, Umeyama, Yui, Nakamura, Takashi, Endo, Rikito, Alam, Mohammad Towfik, Li, Cong, Annan, Dorcas Akuba‐Muhyia, Kikuchi, Hiroshi, Morimoto, Hirofumi, Morimoto, Masahiro, Akiyama, Kosuke, Ohga, Noritaka, Hida, Yasuhiro, Harashima, Hideyoshi, Hida, Kyoko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9128192/ https://www.ncbi.nlm.nih.gov/pubmed/35266253 http://dx.doi.org/10.1111/cas.15323 |
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