Genome-wide promoter methylation profiling in a cellular model of melanoma progression reveals markers of malignancy and metastasis that predict melanoma survival

The epigenetic changes associated with melanoma progression to advanced and metastatic stages are still poorly understood. To shed light on the CpG methylation dynamics during melanoma development, we analyzed the methylome profiles of a four-stage cell line model of melanoma progression: non-tumori...

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Detalles Bibliográficos
Autores principales: Rius, Flávia E., Papaiz, Debora D., Azevedo, Hatylas F. Z., Ayub, Ana Luísa P., Pessoa, Diogo O., Oliveira, Tiago F., Loureiro, Ana Paula M., Andrade, Fernando, Fujita, André, Reis, Eduardo M., Mason, Christopher E., Jasiulionis, Miriam G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9128240/
https://www.ncbi.nlm.nih.gov/pubmed/35606887
http://dx.doi.org/10.1186/s13148-022-01291-x

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