The progress in quantitative evaluation of callus during distraction osteogenesis

The manual monitoring of callus with digital radiography (X-ray) is the primary bone healing evaluation, assessing the number of bridged callus formations. However, this method is subjective and nonquantitative. Recently, several quantitative monitoring methods, which could assess the recovery of th...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Qi, Liu, Ze, Guo, Hongbin, Liang, Jieyu, Zhang, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9128294/
https://www.ncbi.nlm.nih.gov/pubmed/35610718
http://dx.doi.org/10.1186/s12891-022-05458-8
_version_ 1784712534525214720
author Liu, Qi
Liu, Ze
Guo, Hongbin
Liang, Jieyu
Zhang, Yi
author_facet Liu, Qi
Liu, Ze
Guo, Hongbin
Liang, Jieyu
Zhang, Yi
author_sort Liu, Qi
collection PubMed
description The manual monitoring of callus with digital radiography (X-ray) is the primary bone healing evaluation, assessing the number of bridged callus formations. However, this method is subjective and nonquantitative. Recently, several quantitative monitoring methods, which could assess the recovery of the structure and biomechanical properties of the callus at different stages and the process of bone healing, have been extensively investigated. These methods could reflect the bone mineral content (BMC), bone mineral density (BMD), stiffness, callus and bone metabolism at the site of bone lengthening. In this review, we comprehensively summarized the latest techniques for evaluating bone healing during distraction osteogenesis (DO): 1) digital radiography; 2) dual-energy X-ray scanning; 3) ultrasound; 4) quantitative computed tomography; 5) biomechanical evaluation; and 6) biochemical markers. This evidence will provide novel and significant information for evaluating bone healing during DO in the future.
format Online
Article
Text
id pubmed-9128294
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-91282942022-05-25 The progress in quantitative evaluation of callus during distraction osteogenesis Liu, Qi Liu, Ze Guo, Hongbin Liang, Jieyu Zhang, Yi BMC Musculoskelet Disord Review The manual monitoring of callus with digital radiography (X-ray) is the primary bone healing evaluation, assessing the number of bridged callus formations. However, this method is subjective and nonquantitative. Recently, several quantitative monitoring methods, which could assess the recovery of the structure and biomechanical properties of the callus at different stages and the process of bone healing, have been extensively investigated. These methods could reflect the bone mineral content (BMC), bone mineral density (BMD), stiffness, callus and bone metabolism at the site of bone lengthening. In this review, we comprehensively summarized the latest techniques for evaluating bone healing during distraction osteogenesis (DO): 1) digital radiography; 2) dual-energy X-ray scanning; 3) ultrasound; 4) quantitative computed tomography; 5) biomechanical evaluation; and 6) biochemical markers. This evidence will provide novel and significant information for evaluating bone healing during DO in the future. BioMed Central 2022-05-24 /pmc/articles/PMC9128294/ /pubmed/35610718 http://dx.doi.org/10.1186/s12891-022-05458-8 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Review
Liu, Qi
Liu, Ze
Guo, Hongbin
Liang, Jieyu
Zhang, Yi
The progress in quantitative evaluation of callus during distraction osteogenesis
title The progress in quantitative evaluation of callus during distraction osteogenesis
title_full The progress in quantitative evaluation of callus during distraction osteogenesis
title_fullStr The progress in quantitative evaluation of callus during distraction osteogenesis
title_full_unstemmed The progress in quantitative evaluation of callus during distraction osteogenesis
title_short The progress in quantitative evaluation of callus during distraction osteogenesis
title_sort progress in quantitative evaluation of callus during distraction osteogenesis
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9128294/
https://www.ncbi.nlm.nih.gov/pubmed/35610718
http://dx.doi.org/10.1186/s12891-022-05458-8
work_keys_str_mv AT liuqi theprogressinquantitativeevaluationofcallusduringdistractionosteogenesis
AT liuze theprogressinquantitativeevaluationofcallusduringdistractionosteogenesis
AT guohongbin theprogressinquantitativeevaluationofcallusduringdistractionosteogenesis
AT liangjieyu theprogressinquantitativeevaluationofcallusduringdistractionosteogenesis
AT zhangyi theprogressinquantitativeevaluationofcallusduringdistractionosteogenesis
AT liuqi progressinquantitativeevaluationofcallusduringdistractionosteogenesis
AT liuze progressinquantitativeevaluationofcallusduringdistractionosteogenesis
AT guohongbin progressinquantitativeevaluationofcallusduringdistractionosteogenesis
AT liangjieyu progressinquantitativeevaluationofcallusduringdistractionosteogenesis
AT zhangyi progressinquantitativeevaluationofcallusduringdistractionosteogenesis

Ejemplares similares