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COVID-19 Presenting as a Seizure: A Kenyan Case Report

The new coronavirus quickly spread throughout the world in late 2019 and became a pandemic in early 2020. The most common symptoms observed are fever, dry cough, loss of taste and smell, and respiratory distress. Other rarer complications can involve the cardiovascular, gastrointestinal, or neurolog...

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Autores principales: Raza, Syed Moosa, Ebrahim, Farah, Ekea, Herman, Ali, Sayed K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9128310/
https://www.ncbi.nlm.nih.gov/pubmed/35637806
http://dx.doi.org/10.7759/cureus.24431
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author Raza, Syed Moosa
Ebrahim, Farah
Ekea, Herman
Ali, Sayed K
author_facet Raza, Syed Moosa
Ebrahim, Farah
Ekea, Herman
Ali, Sayed K
author_sort Raza, Syed Moosa
collection PubMed
description The new coronavirus quickly spread throughout the world in late 2019 and became a pandemic in early 2020. The most common symptoms observed are fever, dry cough, loss of taste and smell, and respiratory distress. Other rarer complications can involve the cardiovascular, gastrointestinal, or neurological systems. Of the neurological complications, epileptic seizures are a subject of particular interest due to their relatively unknown and widespread etiologies. It is understood that the entry or production of pro-inflammatory cytokines during a COVID-19 infection can result in neurotransmitter modulation and ion channel dysfunction, leading to neuronal hyperexcitability, presenting as seizures. To the best of our knowledge, we present the first case in sub-Saharan Africa of a COVID-19 positive patient presenting to our institution with a reported seizure followed by confusion. Our case highlights the need to broaden our differential diagnosis to include COVID-19 infections in patients presenting with seizures.
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spelling pubmed-91283102022-05-29 COVID-19 Presenting as a Seizure: A Kenyan Case Report Raza, Syed Moosa Ebrahim, Farah Ekea, Herman Ali, Sayed K Cureus Internal Medicine The new coronavirus quickly spread throughout the world in late 2019 and became a pandemic in early 2020. The most common symptoms observed are fever, dry cough, loss of taste and smell, and respiratory distress. Other rarer complications can involve the cardiovascular, gastrointestinal, or neurological systems. Of the neurological complications, epileptic seizures are a subject of particular interest due to their relatively unknown and widespread etiologies. It is understood that the entry or production of pro-inflammatory cytokines during a COVID-19 infection can result in neurotransmitter modulation and ion channel dysfunction, leading to neuronal hyperexcitability, presenting as seizures. To the best of our knowledge, we present the first case in sub-Saharan Africa of a COVID-19 positive patient presenting to our institution with a reported seizure followed by confusion. Our case highlights the need to broaden our differential diagnosis to include COVID-19 infections in patients presenting with seizures. Cureus 2022-04-24 /pmc/articles/PMC9128310/ /pubmed/35637806 http://dx.doi.org/10.7759/cureus.24431 Text en Copyright © 2022, Raza et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Raza, Syed Moosa
Ebrahim, Farah
Ekea, Herman
Ali, Sayed K
COVID-19 Presenting as a Seizure: A Kenyan Case Report
title COVID-19 Presenting as a Seizure: A Kenyan Case Report
title_full COVID-19 Presenting as a Seizure: A Kenyan Case Report
title_fullStr COVID-19 Presenting as a Seizure: A Kenyan Case Report
title_full_unstemmed COVID-19 Presenting as a Seizure: A Kenyan Case Report
title_short COVID-19 Presenting as a Seizure: A Kenyan Case Report
title_sort covid-19 presenting as a seizure: a kenyan case report
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9128310/
https://www.ncbi.nlm.nih.gov/pubmed/35637806
http://dx.doi.org/10.7759/cureus.24431
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