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Transcriptome-Wide Association Studies and Integration Analysis of mRNA Expression Profiles Identify Candidate Genes and Pathways Associated With Ankylosing Spondylitis

This study aimed to identify susceptibility genes and pathways associated with ankylosing spondylitis (AS) by integrating whole transcriptome-wide association study (TWAS) analysis and mRNA expression profiling data. AS genome-wide association study (GWAS) summary data from the large GWAS database w...

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Detalles Bibliográficos
Autores principales: Feng, Ruoyang, Lu, Mengnan, Liu, Lin, Xu, Ke, Xu, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9128383/
https://www.ncbi.nlm.nih.gov/pubmed/35619696
http://dx.doi.org/10.3389/fimmu.2022.814303