Amyloid pathology but not APOE ε4 status is permissive for tau-related hippocampal dysfunction

We investigated whether the impact of tau-pathology on memory performance and on hippocampal/medial temporal memory function in non-demented individuals depends on the presence of amyloid pathology, irrespective of diagnostic clinical stage. We conducted a cross-sectional analysis of the observation...

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Detalles Bibliográficos
Autores principales: Düzel, Emrah, Ziegler, Gabriel, Berron, David, Maass, Anne, Schütze, Hartmut, Cardenas-Blanco, Arturo, Glanz, Wenzel, Metzger, Coraline, Dobisch, Laura, Reuter, Martin, Spottke, Annika, Brosseron, Frederic, Fliessbach, Klaus, Heneka, Michael T, Laske, Christoph, Peters, Oliver, Priller, Josef, Spruth, Eike Jakob, Ramirez, Alfredo, Speck, Oliver, Schneider, Anja, Teipel, Stefan, Kilimann, Ingo, Jens, Wiltfang, Schott, Björn-Hendrik, Preis, Lukas, Gref, Daria, Maier, Franziska, Munk, Matthias H, Roy, Nina, Ballarini, Tomasso, Yakupov, Renat, Haynes, John Dylan, Dechent, Peter, Scheffler, Klaus, Wagner, Michael, Jessen, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9128811/
https://www.ncbi.nlm.nih.gov/pubmed/35352105
http://dx.doi.org/10.1093/brain/awab405

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