Cargando…

Participation in a Prospective Cohort Study on Melanoma did not Affect the Incidence and Mortality of the Studied Disease

Prospective observational studies have shown previously that study participants have lower morbidity and mortality than non-participants. The aim of the current study was to determine whether participants in a prospective cohort study on melanoma have a different incidence and mortality of melanoma...

Descripción completa

Detalles Bibliográficos
Autores principales: INGVAR, Åsa, OLSSON, Håkan, BROBERG, Per, ISAKSSON, Karolin, INGVAR, Christian, NIELSEN, Kari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Publication of Acta Dermato-Venereologica 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9128912/
https://www.ncbi.nlm.nih.gov/pubmed/31663602
http://dx.doi.org/10.2340/00015555-3362
_version_ 1784712645571510272
author INGVAR, Åsa
OLSSON, Håkan
BROBERG, Per
ISAKSSON, Karolin
INGVAR, Christian
NIELSEN, Kari
author_facet INGVAR, Åsa
OLSSON, Håkan
BROBERG, Per
ISAKSSON, Karolin
INGVAR, Christian
NIELSEN, Kari
author_sort INGVAR, Åsa
collection PubMed
description Prospective observational studies have shown previously that study participants have lower morbidity and mortality than non-participants. The aim of the current study was to determine whether participants in a prospective cohort study on melanoma have a different incidence and mortality of melanoma compared with non-participants and the background population. Information was collected from Swedish National Registers on participants (n = 30,501) and non-participants (n = 10,499) in the “Melanoma In Southern Sweden” (MISS) study and the background population (n = 243,032). Hazard ratios were calculated for overall incidence of cancer and melanoma, and all-cause and melanoma-specific mortality, using Cox regression. Participants had a lower overall incidence of cancer and all-cause mortality than non-participants and the background population. There was no difference in incidence of melanoma or melanoma-specific characteristics between participants and the background population. In conclusion, participants in the MISS study have a slightly better general health, but are a representative sample of the population with regard to studies of melanoma risk factors.
format Online
Article
Text
id pubmed-9128912
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Society for Publication of Acta Dermato-Venereologica
record_format MEDLINE/PubMed
spelling pubmed-91289122022-10-20 Participation in a Prospective Cohort Study on Melanoma did not Affect the Incidence and Mortality of the Studied Disease INGVAR, Åsa OLSSON, Håkan BROBERG, Per ISAKSSON, Karolin INGVAR, Christian NIELSEN, Kari Acta Derm Venereol Investigative Report Prospective observational studies have shown previously that study participants have lower morbidity and mortality than non-participants. The aim of the current study was to determine whether participants in a prospective cohort study on melanoma have a different incidence and mortality of melanoma compared with non-participants and the background population. Information was collected from Swedish National Registers on participants (n = 30,501) and non-participants (n = 10,499) in the “Melanoma In Southern Sweden” (MISS) study and the background population (n = 243,032). Hazard ratios were calculated for overall incidence of cancer and melanoma, and all-cause and melanoma-specific mortality, using Cox regression. Participants had a lower overall incidence of cancer and all-cause mortality than non-participants and the background population. There was no difference in incidence of melanoma or melanoma-specific characteristics between participants and the background population. In conclusion, participants in the MISS study have a slightly better general health, but are a representative sample of the population with regard to studies of melanoma risk factors. Society for Publication of Acta Dermato-Venereologica 2020-01-07 /pmc/articles/PMC9128912/ /pubmed/31663602 http://dx.doi.org/10.2340/00015555-3362 Text en © 2020 Acta Dermato-Venereologica https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the CC BY-NC license
spellingShingle Investigative Report
INGVAR, Åsa
OLSSON, Håkan
BROBERG, Per
ISAKSSON, Karolin
INGVAR, Christian
NIELSEN, Kari
Participation in a Prospective Cohort Study on Melanoma did not Affect the Incidence and Mortality of the Studied Disease
title Participation in a Prospective Cohort Study on Melanoma did not Affect the Incidence and Mortality of the Studied Disease
title_full Participation in a Prospective Cohort Study on Melanoma did not Affect the Incidence and Mortality of the Studied Disease
title_fullStr Participation in a Prospective Cohort Study on Melanoma did not Affect the Incidence and Mortality of the Studied Disease
title_full_unstemmed Participation in a Prospective Cohort Study on Melanoma did not Affect the Incidence and Mortality of the Studied Disease
title_short Participation in a Prospective Cohort Study on Melanoma did not Affect the Incidence and Mortality of the Studied Disease
title_sort participation in a prospective cohort study on melanoma did not affect the incidence and mortality of the studied disease
topic Investigative Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9128912/
https://www.ncbi.nlm.nih.gov/pubmed/31663602
http://dx.doi.org/10.2340/00015555-3362
work_keys_str_mv AT ingvarasa participationinaprospectivecohortstudyonmelanomadidnotaffecttheincidenceandmortalityofthestudieddisease
AT olssonhakan participationinaprospectivecohortstudyonmelanomadidnotaffecttheincidenceandmortalityofthestudieddisease
AT brobergper participationinaprospectivecohortstudyonmelanomadidnotaffecttheincidenceandmortalityofthestudieddisease
AT isakssonkarolin participationinaprospectivecohortstudyonmelanomadidnotaffecttheincidenceandmortalityofthestudieddisease
AT ingvarchristian participationinaprospectivecohortstudyonmelanomadidnotaffecttheincidenceandmortalityofthestudieddisease
AT nielsenkari participationinaprospectivecohortstudyonmelanomadidnotaffecttheincidenceandmortalityofthestudieddisease
AT participationinaprospectivecohortstudyonmelanomadidnotaffecttheincidenceandmortalityofthestudieddisease