Guanine Deaminase Stimulates Ultraviolet-induced Keratinocyte Senescence in Seborrhoeic Keratosis via Guanine Metabolites

DNA damage and oxidative stress play a critical role in photoageing. Seborrhoeic keratosis (SK) affects sunlight-exposed sites in aged individuals. This study examined the mechanism of photoageing in SK. The guanine deaminase gene, which is involved in purine metabolism, was upregulated with uric ac...

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Detalles Bibliográficos
Autores principales: CHEONG, Kyung Ah, LEE, Ai-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Publication of Acta Dermato-Venereologica 2020
Materias:
Investigative Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9128948/
https://www.ncbi.nlm.nih.gov/pubmed/32215662
http://dx.doi.org/10.2340/00015555-3473

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