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Treatment and Burden of Disease in a Cohort of Patients with Prurigo Nodularis: A Survey-based Study
Prurigo nodularis is a pruritic dermatosis with poor treatment options. To describe treatment patterns, comorbidities, pruritus, and quality of life a survey was administered to 92 patients with prurigo nodularis. A total of 52 patients completed the survey. The most frequently used treatments were...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Society for Publication of Acta Dermato-Venereologica
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9128953/ https://www.ncbi.nlm.nih.gov/pubmed/32215661 http://dx.doi.org/10.2340/00015555-3471 |
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author | TODBERG, Tanja ZACHARIAE, Claus SKOV, Lone |
author_facet | TODBERG, Tanja ZACHARIAE, Claus SKOV, Lone |
author_sort | TODBERG, Tanja |
collection | PubMed |
description | Prurigo nodularis is a pruritic dermatosis with poor treatment options. To describe treatment patterns, comorbidities, pruritus, and quality of life a survey was administered to 92 patients with prurigo nodularis. A total of 52 patients completed the survey. The most frequently used treatments were topical corticosteroids, which were prescribed to 49/52 patients, with positive effect in 13/49. A total of 46/52 patients were treated with ultraviolet B, and 9/46 reported a positive effect. A positive effect was reported for topical corticosteroids under occlusion in 21/40, for zinc dressing treatment in 17/37, for steroid injection in 9/14, for methotrexate in 5/16, and for thalidomide in 4/12 of treated patients. Thirty-six patients reported a Pittsburgh Sleep Quality Index >5, indicating poor sleep. Patients with prurigo nodularis are severely bothered by pruritus negatively affecting quality of life. Various treatments are prescribed; most frequently topical corticosteroids and ultraviolet B. Surprisingly, patients reported topical corticosteroids under occlusion, zinc-dressing treatment and steroid injection as the most effective. |
format | Online Article Text |
id | pubmed-9128953 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Society for Publication of Acta Dermato-Venereologica |
record_format | MEDLINE/PubMed |
spelling | pubmed-91289532022-10-20 Treatment and Burden of Disease in a Cohort of Patients with Prurigo Nodularis: A Survey-based Study TODBERG, Tanja ZACHARIAE, Claus SKOV, Lone Acta Derm Venereol Clinical Report Prurigo nodularis is a pruritic dermatosis with poor treatment options. To describe treatment patterns, comorbidities, pruritus, and quality of life a survey was administered to 92 patients with prurigo nodularis. A total of 52 patients completed the survey. The most frequently used treatments were topical corticosteroids, which were prescribed to 49/52 patients, with positive effect in 13/49. A total of 46/52 patients were treated with ultraviolet B, and 9/46 reported a positive effect. A positive effect was reported for topical corticosteroids under occlusion in 21/40, for zinc dressing treatment in 17/37, for steroid injection in 9/14, for methotrexate in 5/16, and for thalidomide in 4/12 of treated patients. Thirty-six patients reported a Pittsburgh Sleep Quality Index >5, indicating poor sleep. Patients with prurigo nodularis are severely bothered by pruritus negatively affecting quality of life. Various treatments are prescribed; most frequently topical corticosteroids and ultraviolet B. Surprisingly, patients reported topical corticosteroids under occlusion, zinc-dressing treatment and steroid injection as the most effective. Society for Publication of Acta Dermato-Venereologica 2020-04-21 /pmc/articles/PMC9128953/ /pubmed/32215661 http://dx.doi.org/10.2340/00015555-3471 Text en © 2020 Acta Dermato-Venereologica https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the CC BY-NC license |
spellingShingle | Clinical Report TODBERG, Tanja ZACHARIAE, Claus SKOV, Lone Treatment and Burden of Disease in a Cohort of Patients with Prurigo Nodularis: A Survey-based Study |
title | Treatment and Burden of Disease in a Cohort of Patients with Prurigo Nodularis: A Survey-based Study |
title_full | Treatment and Burden of Disease in a Cohort of Patients with Prurigo Nodularis: A Survey-based Study |
title_fullStr | Treatment and Burden of Disease in a Cohort of Patients with Prurigo Nodularis: A Survey-based Study |
title_full_unstemmed | Treatment and Burden of Disease in a Cohort of Patients with Prurigo Nodularis: A Survey-based Study |
title_short | Treatment and Burden of Disease in a Cohort of Patients with Prurigo Nodularis: A Survey-based Study |
title_sort | treatment and burden of disease in a cohort of patients with prurigo nodularis: a survey-based study |
topic | Clinical Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9128953/ https://www.ncbi.nlm.nih.gov/pubmed/32215661 http://dx.doi.org/10.2340/00015555-3471 |
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