The importance of offering early genetic testing in everyone with amyotrophic lateral sclerosis

Several genetically-targeted therapies are being developed for ALS. Research is increasingly supportive of a greater incidence of clinically actionable variants in sporadic ALS than previously reported. Salmon et al. outline the need to improve access, and offer genetic testing to all people diagnos...

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Autores principales: Salmon, Kristiana, Kiernan, Matthew C., Kim, Seung H., Andersen, Peter M., Chio, Adriano, van den Berg, Leonard H., Van Damme, Philip, Al-Chalabi, Ammar, Lillo, Patricia, Andrews, Jinsy A., Genge, Angela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Special Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9129091/
https://www.ncbi.nlm.nih.gov/pubmed/35020823
http://dx.doi.org/10.1093/brain/awab472
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author Salmon, Kristiana
Kiernan, Matthew C.
Kim, Seung H.
Andersen, Peter M.
Chio, Adriano
van den Berg, Leonard H.
Van Damme, Philip
Al-Chalabi, Ammar
Lillo, Patricia
Andrews, Jinsy A.
Genge, Angela
author_facet Salmon, Kristiana
Kiernan, Matthew C.
Kim, Seung H.
Andersen, Peter M.
Chio, Adriano
van den Berg, Leonard H.
Van Damme, Philip
Al-Chalabi, Ammar
Lillo, Patricia
Andrews, Jinsy A.
Genge, Angela
author_sort Salmon, Kristiana
collection PubMed
description Several genetically-targeted therapies are being developed for ALS. Research is increasingly supportive of a greater incidence of clinically actionable variants in sporadic ALS than previously reported. Salmon et al. outline the need to improve access, and offer genetic testing to all people diagnosed with ALS.
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spelling pubmed-91290912022-05-25 The importance of offering early genetic testing in everyone with amyotrophic lateral sclerosis Salmon, Kristiana Kiernan, Matthew C. Kim, Seung H. Andersen, Peter M. Chio, Adriano van den Berg, Leonard H. Van Damme, Philip Al-Chalabi, Ammar Lillo, Patricia Andrews, Jinsy A. Genge, Angela Brain Special Commentary Several genetically-targeted therapies are being developed for ALS. Research is increasingly supportive of a greater incidence of clinically actionable variants in sporadic ALS than previously reported. Salmon et al. outline the need to improve access, and offer genetic testing to all people diagnosed with ALS. Oxford University Press 2022-01-10 /pmc/articles/PMC9129091/ /pubmed/35020823 http://dx.doi.org/10.1093/brain/awab472 Text en © The Author(s) 2022. Published by Oxford University Press on behalf of the Guarantors of Brain. https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Special Commentary
Salmon, Kristiana
Kiernan, Matthew C.
Kim, Seung H.
Andersen, Peter M.
Chio, Adriano
van den Berg, Leonard H.
Van Damme, Philip
Al-Chalabi, Ammar
Lillo, Patricia
Andrews, Jinsy A.
Genge, Angela
The importance of offering early genetic testing in everyone with amyotrophic lateral sclerosis
title The importance of offering early genetic testing in everyone with amyotrophic lateral sclerosis
title_full The importance of offering early genetic testing in everyone with amyotrophic lateral sclerosis
title_fullStr The importance of offering early genetic testing in everyone with amyotrophic lateral sclerosis
title_full_unstemmed The importance of offering early genetic testing in everyone with amyotrophic lateral sclerosis
title_short The importance of offering early genetic testing in everyone with amyotrophic lateral sclerosis
title_sort importance of offering early genetic testing in everyone with amyotrophic lateral sclerosis
topic Special Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9129091/
https://www.ncbi.nlm.nih.gov/pubmed/35020823
http://dx.doi.org/10.1093/brain/awab472
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