Cargando…

Massively multiplexed affinity characterization of therapeutic antibodies against SARS-CoV-2 variants

Antibody therapies represent a valuable tool to reduce COVID-19 deaths and hospitalizations. Multiple antibody candidates have been granted emergency use authorization by the Food and Drug Administration and many more are in clinical trials. Most antibody therapies for COVID-19 are engineered to bin...

Descripción completa

Detalles Bibliográficos
Autores principales:	Engelhart, Emily, Lopez, Randolph, Emerson, Ryan, Lin, Charles, Shikany, Colleen, Guion, Daniel, Kelley, Mary, Younger, David
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Brief Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9129155/ https://www.ncbi.nlm.nih.gov/pubmed/35769631 http://dx.doi.org/10.1093/abt/tbac011

Ejemplares similares

A dataset comprised of binding interactions for 104,972 antibodies against a SARS-CoV-2 peptide
por: Engelhart, Emily, et al.
Publicado: (2022)

Machine learning optimization of candidate antibody yields highly diverse sub-nanomolar affinity antibody libraries
por: Li, Lin, et al.
Publicado: (2023)

Multiplex Assessment of Protein Variant Abundance by Massively Parallel Sequencing
por: Matreyek, Kenneth A., et al.
Publicado: (2018)

Measuring the sequence-affinity landscape of antibodies with massively parallel titration curves
por: Adams, Rhys M, et al.
Publicado: (2016)

Multiplexed, High-Sensitivity Measurements of Antibody Affinity Using Interferometric Reflectance Imaging Sensor
por: Marn, Allison M., et al.
Publicado: (2021)

Mobile Affinity Selection Chromatography Analysis of Therapeutic Monoclonal Antibodies
por: Narsimhan, Meena L., et al.
Publicado: (2023)

Epitope mapping of spike identifies variant-resistant antibodies
por: Flemming, Alexandra
Publicado: (2021)

A comparison of unamplified and massively multiplexed PCR amplification for murine antibody repertoire sequencing
por: Rettig, Trisha A., et al.
Publicado: (2018)

Organ Mapping Antibody Panels: a community resource for standardized multiplexed tissue imaging
por: Quardokus, Ellen M., et al.
Publicado: (2023)

Multiplexed protein profiling by sequential affinity capture
por: Ayoglu, Burcu, et al.
Publicado: (2016)

Multiplexed transcriptome discovery of RNA-binding protein binding sites by antibody-barcode eCLIP
por: Lorenz, Daniel A., et al.
Publicado: (2022)

Peptide Affinity Chromatography Applied to Therapeutic Antibodies Purification
por: Barredo-Vacchelli, Gabriela R., et al.
Publicado: (2021)

Massively multiplex single-cell Hi-C
por: Ramani, Vijay, et al.
Publicado: (2017)

Massively multiplex single-molecule oligonucleosome footprinting
por: Abdulhay, Nour J, et al.
Publicado: (2020)

Aptamer BC 007’s Affinity to Specific and Less-Specific Anti-SARS-CoV-2 Neutralizing Antibodies
por: Haberland, Annekathrin, et al.
Publicado: (2021)

SARS-CoV-2 variant evades antibodies whilst maintaining fitness
por: Flemming, Alexandra
Publicado: (2021)

Multiplexed Affinity Measurements of Extracellular Vesicles Binding Kinetics
por: Chiodi, Elisa, et al.
Publicado: (2021)

IgY Antibodies from Birds: A Review on Affinity and Avidity
por: Pacheco, Bianca Lisley Barboza, et al.
Publicado: (2023)

Desktop Nanofabrication with Massively Multiplexed Beam Pen Lithography
por: Liao, Xing, et al.
Publicado: (2013)

Massively multiplexed nucleic acid detection with Cas13
por: Ackerman, Cheri M., et al.
Publicado: (2020)

Massively parallel identification of functionally consequential noncoding genetic variants in undiagnosed rare disease patients
por: McQuerry, Jasmine A., et al.
Publicado: (2022)

Myeloperoxidase anti‐neutrophil cytoplasmic antibody affinity is associated with the formation of neutrophil extracellular traps in the kidney and vasculitis activity in myeloperoxidase anti‐neutrophil cytoplasmic antibody‐associated microscopic polyangiitis
por: Yoshida, Masaharu, et al.
Publicado: (2016)

Increased resistance of SARS-CoV-2 variant P.1 to antibody neutralization
por: Wang, Pengfei, et al.
Publicado: (2021)

Serological fingerprints link antiviral activity of therapeutic antibodies to affinity and concentration
por: Fiedler, Sebastian, et al.
Publicado: (2022)

Wavelength-encoded laser particles for massively multiplexed cell tagging
por: Martino, Nicola, et al.
Publicado: (2019)

Deciphering cell signaling networks with massively multiplexed biosensor barcoding
por: Yang, Jr-Ming, et al.
Publicado: (2021)

Massively-multiplexed epitope mapping techniques for viral antigen discovery
por: Hu, Diya, et al.
Publicado: (2023)

Looking for therapeutic antibodies in next-generation sequencing repositories
por: Krawczyk, Konrad, et al.
Publicado: (2019)

Massively parallel sequencing of Cannabis sativa chloroplast hotspots for forensic typing
por: Roman, Madeline G., et al.
Publicado: (2022)

Affinity improvement of a therapeutic antibody to methamphetamine and amphetamine through structure-based antibody engineering
por: Thakkar, Shraddha, et al.
Publicado: (2014)

The interdependence of antibody C and V regions on specificity and affinity: Significant implications for the engineering of therapeutic antibodies
por: Nosanchuk, Joshua D.
Publicado: (2013)

Multiplexed single-cell 3D spatial gene expression analysis in plant tissue using PHYTOMap
por: Nobori, Tatsuya, et al.
Publicado: (2023)

The Influence of Protein Charge and Molecular Weight on the Affinity of Aptamers
por: Drees, Alissa, et al.
Publicado: (2023)

Human antibodies induce arthritis in mice deficient in the low-affinity inhibitory IgG receptor FcγRIIB
por: Petkova, Stefka B., et al.
Publicado: (2006)

Occam's Razor Need Not Apply: A Case of Concurrent Cryptococcal Meningitis and Primary Central Nervous System Lymphoma in an Human Immunodeficiency Virus/Acquired Immune Deficiency Syndrome Patient
por: Wang, Xiao Jing, et al.
Publicado: (2015)

A multiplex real-time reverse transcription polymerase chain reaction assay for differentiation of classical and variant II strains of avian infectious bronchitis virus
por: Ameen, Sara M., et al.
Publicado: (2022)

Neutralizing Antibody Response of Vaccinees to SARS-CoV-2 Variants
por: Anichini, Gabriele, et al.
Publicado: (2021)

SARS-CoV-2 mRNA vaccine induced higher antibody affinity and IgG titers against variants of concern in post-partum vs non-post-partum women
por: Lee, Youri, et al.
Publicado: (2022)

Transferrin receptor (TfR) trafficking determines brain uptake of TfR antibody affinity variants
por: Bien-Ly, Nga, et al.
Publicado: (2014)

Multiplexed Affinity-Based Separation of Proteins and Cells Using Inertial Microfluidics
por: Sarkar, Aniruddh, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_tjscg8ndfrv0gq6jgsq3mnqlt3