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Prevalence of Hepatitis C in patients with opioid (intravenous) dependence, in a tertiary care hospital of Himachal Pradesh

INTRODUCTION: Blood borne viral infections (hepatitis C, hepatitis B, human immune deficiency virus), constitute a significant public health concern among patients with opioid dependence, especially among intravenous drug users (IDU). AIM: To measure the prevalence of hepatitis C among patients with...

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Autores principales: Gupta, Simran, Sharma, Ravi, Sharma, Nidhi, Rashi, Sharma, Dinesh Dutt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9129428/
http://dx.doi.org/10.4103/0019-5545.341764
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author Gupta, Simran
Sharma, Ravi
Sharma, Nidhi
Rashi,
Sharma, Dinesh Dutt
author_facet Gupta, Simran
Sharma, Ravi
Sharma, Nidhi
Rashi,
Sharma, Dinesh Dutt
author_sort Gupta, Simran
collection PubMed
description INTRODUCTION: Blood borne viral infections (hepatitis C, hepatitis B, human immune deficiency virus), constitute a significant public health concern among patients with opioid dependence, especially among intravenous drug users (IDU). AIM: To measure the prevalence of hepatitis C among patients with intravenous opioid dependence, visiting de-addiction clinic, in a tertiary care hospital in the state of Himachal Pradesh. MATERIAL AND METHOD: A cross-sectional study was conducted between January 2021 and June 2021 at de-addiction clinic, department of Psychiatry, IGMC, Shimla. Socio-demographic and clinical profiles of patients with diagnosis of opioid dependence was entered in a pre-structured performa. All these patients were investigated for HCV antibody using ELISA (enzyme linked immunoassay) test. RESULTS: The study sample comprised of 200 male patients, and majority were between age 21-40 years (96.5%), from nuclear families (57%), urban background (56.5%). One fourth (25.5%) reported suicidal ideation/attempt. Intravenous mode of drug use (IDU) was reported by 121 (60.5%) patients, and majority were from nuclear families (64.46%), urban background (49.59%), and 30.58% reported suicidal ideation/attempt. 29 patients (23.97%) tested positive for hepatitis C infection. CONCLUSION: There is high rate of hepatitis C infection among patients with opioid (intravenous) dependence, at our de-addiction clinic. Future studies with large sample size exploring the high risk behaviour practices and studies with longitudinal design to assess treatment retention, are needed.
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spelling pubmed-91294282022-05-25 Prevalence of Hepatitis C in patients with opioid (intravenous) dependence, in a tertiary care hospital of Himachal Pradesh Gupta, Simran Sharma, Ravi Sharma, Nidhi Rashi, Sharma, Dinesh Dutt Indian J Psychiatry Free Papers Compiled INTRODUCTION: Blood borne viral infections (hepatitis C, hepatitis B, human immune deficiency virus), constitute a significant public health concern among patients with opioid dependence, especially among intravenous drug users (IDU). AIM: To measure the prevalence of hepatitis C among patients with intravenous opioid dependence, visiting de-addiction clinic, in a tertiary care hospital in the state of Himachal Pradesh. MATERIAL AND METHOD: A cross-sectional study was conducted between January 2021 and June 2021 at de-addiction clinic, department of Psychiatry, IGMC, Shimla. Socio-demographic and clinical profiles of patients with diagnosis of opioid dependence was entered in a pre-structured performa. All these patients were investigated for HCV antibody using ELISA (enzyme linked immunoassay) test. RESULTS: The study sample comprised of 200 male patients, and majority were between age 21-40 years (96.5%), from nuclear families (57%), urban background (56.5%). One fourth (25.5%) reported suicidal ideation/attempt. Intravenous mode of drug use (IDU) was reported by 121 (60.5%) patients, and majority were from nuclear families (64.46%), urban background (49.59%), and 30.58% reported suicidal ideation/attempt. 29 patients (23.97%) tested positive for hepatitis C infection. CONCLUSION: There is high rate of hepatitis C infection among patients with opioid (intravenous) dependence, at our de-addiction clinic. Future studies with large sample size exploring the high risk behaviour practices and studies with longitudinal design to assess treatment retention, are needed. Wolters Kluwer - Medknow 2022-03 2022-03-24 /pmc/articles/PMC9129428/ http://dx.doi.org/10.4103/0019-5545.341764 Text en Copyright: © 2022 Indian Journal of Psychiatry https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Free Papers Compiled
Gupta, Simran
Sharma, Ravi
Sharma, Nidhi
Rashi,
Sharma, Dinesh Dutt
Prevalence of Hepatitis C in patients with opioid (intravenous) dependence, in a tertiary care hospital of Himachal Pradesh
title Prevalence of Hepatitis C in patients with opioid (intravenous) dependence, in a tertiary care hospital of Himachal Pradesh
title_full Prevalence of Hepatitis C in patients with opioid (intravenous) dependence, in a tertiary care hospital of Himachal Pradesh
title_fullStr Prevalence of Hepatitis C in patients with opioid (intravenous) dependence, in a tertiary care hospital of Himachal Pradesh
title_full_unstemmed Prevalence of Hepatitis C in patients with opioid (intravenous) dependence, in a tertiary care hospital of Himachal Pradesh
title_short Prevalence of Hepatitis C in patients with opioid (intravenous) dependence, in a tertiary care hospital of Himachal Pradesh
title_sort prevalence of hepatitis c in patients with opioid (intravenous) dependence, in a tertiary care hospital of himachal pradesh
topic Free Papers Compiled
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9129428/
http://dx.doi.org/10.4103/0019-5545.341764
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