An overview of QTc Prolongation with antipsychotics and antidepressants

Many antipsychotics and antidepressants are found to be associated with prolonged QTc interval. Excessive QTc prolongation can result in tachycardias such as torsa de pointes. It is imperative to confidently measure QT interval and to apply appropriate formula to measure corrected QT interval so that at risk patients can be identified and various antipsychotics and antidepressants which are associated with QTc prolongation can be avoided. Developing an approach of lessening the risk at the same time controlling the psychopathology at low resource setting is the mantra.