The DNA sensors AIM2 and IFI16 are SLE autoantigens that bind neutrophil extracellular traps

BACKGROUND: Nucleic acid binding proteins are frequently targeted as autoantigens in systemic lupus erythematosus (SLE) and other interferon (IFN)-linked rheumatic diseases. The AIM-like receptors (ALRs) are IFN-inducible innate sensors that form supramolecular assemblies along double-stranded (ds)D...

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Detalles Bibliográficos
Autores principales: Antiochos, Brendan, Trejo-Zambrano, Daniela, Fenaroli, Paride, Rosenberg, Avi, Baer, Alan, Garg, Archit, Sohn, Jungsan, Li, Jessica, Petri, Michelle, Goldman, Daniel W, Mecoli, Christopher, Casciola-Rosen, Livia, Rosen, Antony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Immunology and Inflammation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9129876/
https://www.ncbi.nlm.nih.gov/pubmed/35608258
http://dx.doi.org/10.7554/eLife.72103

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9129876/
https://www.ncbi.nlm.nih.gov/pubmed/35608258
http://dx.doi.org/10.7554/eLife.72103

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