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Eosinophilic Granulomatosis With Polyangiitis Presenting With Oral Granuloma as the Initial Symptom: A Case Report

Antineutrophil cytoplasmic antibody associated vasculitis includes granulomatosis with polyangiitis, eosinophilic granulomatosis with polyangiitis (EGPA), and microscopic polyangiitis. While EGPA has no specific symptoms, it usually presents as necrotizing vasculitis, eosinophil infiltration of the...

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Autores principales: Lin, Lirong, Yu, Rongjie, Zheng, Luquan, Gong, Shuyu, Yang, Jurong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9129884/
https://www.ncbi.nlm.nih.gov/pubmed/35620723
http://dx.doi.org/10.3389/fmed.2022.842137
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author Lin, Lirong
Yu, Rongjie
Zheng, Luquan
Gong, Shuyu
Yang, Jurong
author_facet Lin, Lirong
Yu, Rongjie
Zheng, Luquan
Gong, Shuyu
Yang, Jurong
author_sort Lin, Lirong
collection PubMed
description Antineutrophil cytoplasmic antibody associated vasculitis includes granulomatosis with polyangiitis, eosinophilic granulomatosis with polyangiitis (EGPA), and microscopic polyangiitis. While EGPA has no specific symptoms, it usually presents as necrotizing vasculitis, eosinophil infiltration of the tissues and organs, and extravascular granuloma formation. Here, we report a patient who had a rare initial presentation of oral granuloma and had been previously misdiagnosed several times at other hospitals. He was finally diagnosed with EGPA and recovered after methylprednisolone and cyclophosphamide treatment. The disease EGPA can present with a rare initial presentation of oral granuloma, methylprednisolone, and cyclophosphamide can be a suitable choice of treatment.
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spelling pubmed-91298842022-05-25 Eosinophilic Granulomatosis With Polyangiitis Presenting With Oral Granuloma as the Initial Symptom: A Case Report Lin, Lirong Yu, Rongjie Zheng, Luquan Gong, Shuyu Yang, Jurong Front Med (Lausanne) Medicine Antineutrophil cytoplasmic antibody associated vasculitis includes granulomatosis with polyangiitis, eosinophilic granulomatosis with polyangiitis (EGPA), and microscopic polyangiitis. While EGPA has no specific symptoms, it usually presents as necrotizing vasculitis, eosinophil infiltration of the tissues and organs, and extravascular granuloma formation. Here, we report a patient who had a rare initial presentation of oral granuloma and had been previously misdiagnosed several times at other hospitals. He was finally diagnosed with EGPA and recovered after methylprednisolone and cyclophosphamide treatment. The disease EGPA can present with a rare initial presentation of oral granuloma, methylprednisolone, and cyclophosphamide can be a suitable choice of treatment. Frontiers Media S.A. 2022-05-10 /pmc/articles/PMC9129884/ /pubmed/35620723 http://dx.doi.org/10.3389/fmed.2022.842137 Text en Copyright © 2022 Lin, Yu, Zheng, Gong and Yang. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Medicine
Lin, Lirong
Yu, Rongjie
Zheng, Luquan
Gong, Shuyu
Yang, Jurong
Eosinophilic Granulomatosis With Polyangiitis Presenting With Oral Granuloma as the Initial Symptom: A Case Report
title Eosinophilic Granulomatosis With Polyangiitis Presenting With Oral Granuloma as the Initial Symptom: A Case Report
title_full Eosinophilic Granulomatosis With Polyangiitis Presenting With Oral Granuloma as the Initial Symptom: A Case Report
title_fullStr Eosinophilic Granulomatosis With Polyangiitis Presenting With Oral Granuloma as the Initial Symptom: A Case Report
title_full_unstemmed Eosinophilic Granulomatosis With Polyangiitis Presenting With Oral Granuloma as the Initial Symptom: A Case Report
title_short Eosinophilic Granulomatosis With Polyangiitis Presenting With Oral Granuloma as the Initial Symptom: A Case Report
title_sort eosinophilic granulomatosis with polyangiitis presenting with oral granuloma as the initial symptom: a case report
topic Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9129884/
https://www.ncbi.nlm.nih.gov/pubmed/35620723
http://dx.doi.org/10.3389/fmed.2022.842137
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