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SMGL-1/NBAS acts as a RAB-8 GEF to regulate unconventional protein secretion

Unconventional protein secretion (UPS) pathways are conserved across species. However, the underlying mechanisms that regulate Golgi-bypassing UPS of integral proteins remain elusive. In this study, we show that RAB-8 and SMGL-1/NBAS are required for the UPS of integral proteins in C. elegans intest...

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Detalles Bibliográficos
Autores principales: Wang, Xianghong, Li, Xinxin, Wang, Junkai, Wang, Jiabin, Hu, Can, Zeng, Jia, Shi, Anbing, Lin, Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9129922/
https://www.ncbi.nlm.nih.gov/pubmed/35604368
http://dx.doi.org/10.1083/jcb.202111125