Low-dose melittin is safe for intravitreal administration and ameliorates inflammation in an experimental model of uveitis

Uveitis is a group of sight-threatening ocular inflammatory disorders, whose mainstay of therapy is associated with severe adverse events, prompting the investigation of alternative treatments. The peptide melittin (MEL) is the major component of Apis mellifera bee venom and presents anti-inflammato...

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Detalles Bibliográficos
Autores principales: Moreira Castro, Brenda Fernanda, Nunes da Silva, Carolina, Barbosa Cordeiro, Lídia Pereira, Pereira de Freitas Cenachi, Sarah, Vasconcelos-Santos, Daniel Vitor, Machado, Renes Resende, Dias Heneine, Luiz Guilherme, Silva, Luciana Maria, Silva-Cunha, Armando, Fialho, Silvia Ligório
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9130091/
https://www.ncbi.nlm.nih.gov/pubmed/35647524
http://dx.doi.org/10.1016/j.crphar.2022.100107

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