Slowly expanding lesions relate to persisting black-holes and clinical outcomes in relapse-onset multiple sclerosis

BACKGROUND: Slowly expanding lesions (SELs) are MRI markers of chronic active lesions in multiple sclerosis (MS). T1-hypointense black holes, and reductions in magnetization transfer ratio (MTR) are pathologically correlated with myelin and axonal loss. While all associated with progressive MS, the...

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Detalles Bibliográficos
Autores principales: Calvi, Alberto, Tur, Carmen, Chard, Declan, Stutters, Jonathan, Ciccarelli, Olga, Cortese, Rosa, Battaglini, Marco, Pietroboni, Anna, De Riz, Milena, Galimberti, Daniela, Scarpini, Elio, De Stefano, Nicola, Prados, Ferran, Barkhof, Frederik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9130104/
https://www.ncbi.nlm.nih.gov/pubmed/35598462
http://dx.doi.org/10.1016/j.nicl.2022.103048

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