Identification of hereditary breast and ovarian cancer germline variants in Granada (Spain): NGS perspective

The aim of this study was to assess the prevalence of germline variants in cancer-predisposing genes by either targeted (BRCA1/2) or multigene NGS panel in a high-risk Hereditary Breast and Ovarian Cancer (HBOC) cohort. Samples from 824 Caucasian probands were retrospectively collected and the impac...

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Detalles Bibliográficos
Autores principales: Molina-Zayas, María, Garrido-Navas, Carmen, García-Puche, Jose Luis, Barwell, Julian, Pedrinaci, Susana, Atienza, Margarita Martínez, García-Linares, Susana, de Haro-Muñoz, Tomás, Lorente, Jose Antonio, Serrano, M. Jose, Poyatos-Andújar, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9130174/
https://www.ncbi.nlm.nih.gov/pubmed/35451682
http://dx.doi.org/10.1007/s00438-022-01891-5

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