Lipid metabolism dysfunction induced by age-dependent DNA methylation accelerates aging

Epigenetic alterations and metabolic dysfunction are two hallmarks of aging. However, the mechanism of how their interaction regulates aging, particularly in mammals, remains largely unknown. Here we show ELOVL fatty acid elongase 2 (Elovl2), a gene whose epigenetic alterations are most highly corre...

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Detalles Bibliográficos
Autores principales: Li, Xin, Wang, Jiaqiang, Wang, LeYun, Gao, Yuanxu, Feng, Guihai, Li, Gen, Zou, Jun, Yu, Meixin, Li, Yu Fei, Liu, Chao, Yuan, Xue Wei, Zhao, Ling, Ouyang, Hong, Zhu, Jian-Kang, Li, Wei, Zhou, Qi, Zhang, Kang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9130224/
https://www.ncbi.nlm.nih.gov/pubmed/35610223
http://dx.doi.org/10.1038/s41392-022-00964-6

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