Anoctamin 1 controls bone resorption by coupling Cl(−) channel activation with RANKL-RANK signaling transduction

Osteoclast over-activation leads to bone loss and chloride homeostasis is fundamental importance for osteoclast function. The calcium-activated chloride channel Anoctamin 1 (also known as TMEM16A) is an important chloride channel involved in many physiological processes. However, its role in osteocl...

Descripción completa

Detalles Bibliográficos
Autores principales: Sun, Weijia, Guo, Shuai, Li, Yuheng, Li, JianWei, Liu, Caizhi, Chen, Yafei, Wang, Xuzhao, Tan, Yingjun, Tian, Hua, Wang, Cheng, Du, Ruikai, Zhong, Guohui, Shi, Sai, Ma, Biao, Qu, Chang, Fu, Jingxuan, Jin, Xiaoyan, Zhao, Dingsheng, Zhan, Yong, Ling, Shukuan, An, Hailong, Li, Yingxian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9130328/
https://www.ncbi.nlm.nih.gov/pubmed/35610255
http://dx.doi.org/10.1038/s41467-022-30625-9

Ejemplares similares

Ejemplares similares