Alcohol-Induced Glycolytic Shift in Alveolar Macrophages Is Mediated by Hypoxia-Inducible Factor-1 Alpha

Excessive alcohol use increases the risk of developing respiratory infections partially due to impaired alveolar macrophage (AM) phagocytic capacity. Previously, we showed that chronic ethanol (EtOH) exposure led to mitochondrial derangements and diminished oxidative phosphorylation in AM. Since oxi...

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Detalles Bibliográficos
Autores principales: Morris, Niya L., Michael, David N., Crotty, Kathryn M., Chang, Sarah S., Yeligar, Samantha M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9130492/
https://www.ncbi.nlm.nih.gov/pubmed/35634337
http://dx.doi.org/10.3389/fimmu.2022.865492

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9130492/
https://www.ncbi.nlm.nih.gov/pubmed/35634337
http://dx.doi.org/10.3389/fimmu.2022.865492

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