Synthesis of isomeric 4-(N-methyltetrazolylamino)-2-phenyl-4H-thiopyrano[2,3-b]quinoline-3-carbaldehydes and 4-hydroxy-2-phenyl-4H-thiopyrano[2,3-b]quinoline-3-carbaldehyde based on tandem thiol-Michael and (aza)-Morita–Baylis–Hillman reactions and an in vitro study of the activity of the obtained compounds against influenza virus

[Image: see text] 3-{[(1-Methyl-1H-tetrazol-5-yl)imino]methyl}quinoline-2-thiol and 3-{[(2-methyl-2H-tetrazol-5-yl)imino]methyl}quinoline-2-thiol were synthesized. The sequence of the thiol-Michael reaction and the (aza)-Morita–Baylis–Hillman reaction yielded 4-[(1-methyl-1H-tetrazol-5-yl)amino]-2-p...

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Autores principales: Khramchikhin, Andrey V., Skryl’nikova, Mariya А., Pavlyukova, Yuliya N., Zarubaev, Vladimir V., Esaulkova, Yana L., Muryleva, Anna А., Shmanyova, Nadezhda T., Danagulyan, Gevorg G., Ostrovskii, Vladimir А.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9130687/
https://www.ncbi.nlm.nih.gov/pubmed/35645404
http://dx.doi.org/10.1007/s10593-022-03083-w

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