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Baricitinib attenuates the proinflammatory phase of COVID-19 driven by lung-infiltrating monocytes

SARS-CoV-2-infected subjects are generally asymptomatic during initial viral replication but may suffer severe immunopathology after the virus has receded and monocytes have infiltrated the airways. In bronchoalveolar lavage fluid from severe COVID-19 patients, monocytes express mRNA encoding inflam...

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Detalles Bibliográficos
Autores principales: Dobosh, Brian, Zandi, Keivan, Giraldo, Diego Moncada, Goh, Shu Ling, Musall, Kathryn, Aldeco, Milagros, LeCher, Julia, Giacalone, Vincent D., Yang, Junkai, Eddins, Devon J., Bhasin, Manoj, Ghosn, Eliver, Sukhatme, Vikas, Schinazi, Raymond F., Tirouvanziam, Rabindra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9130711/
https://www.ncbi.nlm.nih.gov/pubmed/35688145
http://dx.doi.org/10.1016/j.celrep.2022.110945