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Baricitinib attenuates the proinflammatory phase of COVID-19 driven by lung-infiltrating monocytes
SARS-CoV-2-infected subjects are generally asymptomatic during initial viral replication but may suffer severe immunopathology after the virus has receded and monocytes have infiltrated the airways. In bronchoalveolar lavage fluid from severe COVID-19 patients, monocytes express mRNA encoding inflam...
Autores principales: | Dobosh, Brian, Zandi, Keivan, Giraldo, Diego Moncada, Goh, Shu Ling, Musall, Kathryn, Aldeco, Milagros, LeCher, Julia, Giacalone, Vincent D., Yang, Junkai, Eddins, Devon J., Bhasin, Manoj, Ghosn, Eliver, Sukhatme, Vikas, Schinazi, Raymond F., Tirouvanziam, Rabindra |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Author(s).
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9130711/ https://www.ncbi.nlm.nih.gov/pubmed/35688145 http://dx.doi.org/10.1016/j.celrep.2022.110945 |
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