Synthesis of 2-Nitro-2,3-Unsaturated Glycosides by a Nanomagnetic Catalyst Fe(3)O(4)@C@Fe(III)

A sustainable magnetic core-shell nanocatalyst Fe(3)O(4)@C@Fe(III) was successfully applied in the synthesis of a series of 2-nitro-2,3-unsaturated O-glycosides with excellent yields (up to 89%) and high stereoselectivity (α:β > 19:1). The substrate ranges are widely applicable, including differe...

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Detalles Bibliográficos
Autores principales: Yang, Yu, Jiang, Nan, Mei, Yuling, Ding, Zekun, Zhang, Jianbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9130751/
https://www.ncbi.nlm.nih.gov/pubmed/35646809
http://dx.doi.org/10.3389/fchem.2022.865012
Descripción
Sumario:A sustainable magnetic core-shell nanocatalyst Fe(3)O(4)@C@Fe(III) was successfully applied in the synthesis of a series of 2-nitro-2,3-unsaturated O-glycosides with excellent yields (up to 89%) and high stereoselectivity (α:β > 19:1). The substrate ranges are widely applicable, including different kinds of alcohols and even structurally complex acceptors. In addition, phenols could be applied in good yields. Moreover, the catalyst could be easily separated from the reaction by the application of an external magnetic force and reused a minimum of five times without any significant decrease in catalytic performance.

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