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Recent Advances in the Structural Biology of the Volume-Regulated Anion Channel LRRC8

Members of the leucine-rich repeat-containing 8 (LRRC8) protein family, composed of five LRRC8A-E isoforms, are pore-forming components of the volume-regulated anion channel (VRAC), which is activated by cell swelling and releases chloride ions (Cl(−)) or other osmolytes to counteract cell swelling....

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Detalles Bibliográficos
Autores principales:	Kasuya, Go, Nureki, Osamu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9130832/ https://www.ncbi.nlm.nih.gov/pubmed/35645818 http://dx.doi.org/10.3389/fphar.2022.896532

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