Bacteria‐Elicited Specific Thrombosis Utilizing Acid‐Induced Cytolysin A Expression to Enable Potent Tumor Therapy

Given the special microenvironment of solid tumors, live microorganisms have emerged as drug delivery vehicles and therapeutic agents. Here, an acid‐induced therapeutic platform is constructed using attenuated Escherichia coli to express the cytolysin A protein. The bacteria can target and colonize...

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Detalles Bibliográficos
Autores principales: Qin, Wenjun, Xu, Wenxuan, Wang, Longyu, Ren, Debao, Cheng, Yibin, Song, Wen, Jiang, Tao, Ma, Lixin, Zhang, Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9130894/
https://www.ncbi.nlm.nih.gov/pubmed/35411710
http://dx.doi.org/10.1002/advs.202105086

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9130894/
https://www.ncbi.nlm.nih.gov/pubmed/35411710
http://dx.doi.org/10.1002/advs.202105086

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