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The Double-Faceted Role of Leucine-Rich Repeat Kinase 2 in the Immunopathogenesis of Parkinson’s Disease

Leucine-rich repeat kinase 2 (LRRK2) is one of the most common causative genes in Parkinson’s disease (PD). The complex structure of this multiple domains’ protein determines its versatile functions in multiple physiological processes, including migration, autophagy, phagocytosis, and mitochondrial...

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Detalles Bibliográficos
Autores principales: Zhang, Mengfei, Li, Chaoyi, Ren, Jie, Wang, Huakun, Yi, Fang, Wu, Junjiao, Tang, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9131027/
https://www.ncbi.nlm.nih.gov/pubmed/35645775
http://dx.doi.org/10.3389/fnagi.2022.909303