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Extracellular vesicles derived from astrocyte-treated with haFGF(14-154) attenuate Alzheimer phenotype in AD mice

Background: aFGF content in serum and cerebrospinal fluid is increased in Alzheimer's disease (AD) patients and attenuates the activation of astrocytes. Extracellular vesicles (EVs) are a major mediator in astrocyte-neuron communications. Since excessive or persistent reactive astrocytes lead t...

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Detalles Bibliográficos
Autores principales: Peng, Dong, Wang, Youjin, Xiao, Yuanjie, Peng, Mengyuan, Mai, Wanwen, Hu, Bo, Jia, Yanbin, Chen, Hongxia, Yang, Yan, Xiang, Qi, Su, Zhijian, Zhang, Qihao, Huang, Yadong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9131260/
https://www.ncbi.nlm.nih.gov/pubmed/35664060
http://dx.doi.org/10.7150/thno.70951