Sequentially targeting and intervening mutual Polo-like Kinase 1 on CAFs and tumor cells by dual targeting nano-platform for cholangiocarcinoma treatment

Rationale: Synergistic treatment strategies for two or more drugs have gradually developed as the main options in clinics for cholangiocarcinoma (CCA) owing to the complicated crosstalk between the tumor and stroma. However, the different synergetic mechanisms pose great challenges to the dosages an...

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Detalles Bibliográficos
Autores principales: Zhou, Yue, Xu, Lei, Wang, Zhangding, Liu, Hongwen, Zhang, Xiang, Shu, Chuanjun, Zhang, Meng, Wang, Ting, Xu, Xinyun, Pu, Xiaohong, He, Jian, Wang, Pin, Qiu, Yudong, Xu, Guifang, Zou, Xiaoping, Zhu, Yun, Wang, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9131280/
https://www.ncbi.nlm.nih.gov/pubmed/35664077
http://dx.doi.org/10.7150/thno.70557

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