5-HT2B-mediated serotonin activation in enterocytes suppresses colitis-associated cancer initiation and promotes cancer progression

Rationale: Serotonin (5-hydroxytryptamine, 5-HT) is generally considered to be involved in colitis-associated cancer (CAC), but previous research has yielded inconsistent results regarding the effect of 5-HT on CAC. 5-HT2B is one of the receptors of 5-HT, and the receptor is expressed in intestinal...

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Detalles Bibliográficos
Autores principales: Mao, Liyuan, Xin, Fang, Ren, Jie, Xu, Shuai, Huang, Haixia, Zha, Xu, Wen, Xinxin, Gu, Guoqing, Yang, Guang, Cheng, Yuan, Zhang, Chen, Wang, Wei, Liu, Xicheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9131283/
https://www.ncbi.nlm.nih.gov/pubmed/35664068
http://dx.doi.org/10.7150/thno.70762

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