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Structure-Based Discovery of Lipoteichoic Acid Synthase Inhibitors

[Image: see text] Lipoteichoic acid synthase (LtaS) is a key enzyme for the cell wall biosynthesis of Gram-positive bacteria. Gram-positive bacteria that lack lipoteichoic acid (LTA) exhibit impaired cell division and growth defects. Thus, LtaS appears to be an attractive antimicrobial target. The p...

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Detalles Bibliográficos
Autores principales:	Chee Wezen, Xavier, Chandran, Aneesh, Eapen, Rohan Sakariah, Waters, Elaine, Bricio-Moreno, Laura, Tosi, Tommaso, Dolan, Stephen, Millership, Charlotte, Kadioglu, Aras, Gründling, Angelika, Itzhaki, Laura S., Welch, Martin, Rahman, Taufiq
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2022
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9131456/ https://www.ncbi.nlm.nih.gov/pubmed/35533315 http://dx.doi.org/10.1021/acs.jcim.2c00300

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