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Gene alternation of cerebrospinal fluid in patients with leptomeningeal metastases of lung adenocarcinoma using next-generation sequencing

BACKGROUND: Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) provide a better prognosis in EGFR-mutant non-small cell lung cancer (NSCLC). Nevertheless, the outcome of leptomeningeal metastasis (LM) remains poor. In addition, due to limited access to intracranial tumour tissue...

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Detalles Bibliográficos
Autores principales:	Yang, Hainan, Wen, Lei, Pan, Yingying, Shan, Changguo, Hong, Weiping, Wang, Hui, Zhou, Cheng, Cai, Linbo, Zhou, Caicun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9131527/ https://www.ncbi.nlm.nih.gov/pubmed/35614407 http://dx.doi.org/10.1186/s12885-022-09597-y

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