Cargando…

Systematic identification of the lysine lactylation in the protozoan parasite Toxoplasma gondii

BACKGROUND: Lysine lactylation (Kla) is a novelposttranslational modification (PTM) identified in histone and nonhistone proteins of several eukaryotic cells that directly activates gene expression and DNA replication. However, very little is known about the scope and cellular distribution of Kla in...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhao, Wei, Yu, Helin, Liu, Xiaona, Wang, Tingting, Yao, Yinning, Zhou, Qixin, Zheng, Xiaozi, Tan, Feng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9131557/ https://www.ncbi.nlm.nih.gov/pubmed/35610722 http://dx.doi.org/10.1186/s13071-022-05315-6

Ejemplares similares

Investigation of Antiparasitic Activity of Two Marine Natural Products, Estradiol Benzoate, and Octyl Gallate, on Toxoplasma gondii In Vitro
por: Lu, Daiqiang, et al.
Publicado: (2022)

Toxoplasma TgAtg8-TgAtg3 Interaction Primarily Contributes to Apicoplast Inheritance and Parasite Growth in Tachyzoite
por: Cheng, Linyan, et al.
Publicado: (2022)

Protein Lactylation Critically Regulates Energy Metabolism in the Protozoan Parasite Trypanosoma brucei
por: Zhang, Naiwen, et al.
Publicado: (2021)

MyosinA is a druggable target in the widespread protozoan parasite Toxoplasma gondii
por: Kelsen, Anne, et al.
Publicado: (2023)

Transcriptional regulation of two stage-specifically expressed genes in the protozoan parasite Toxoplasma gondii
por: Kibe, Michael K., et al.
Publicado: (2005)

Protozoan Parasite Toxoplasma gondii Manipulates Mate Choice in Rats by Enhancing Attractiveness of Males
por: Dass, Shantala Arundathi Hari, et al.
Publicado: (2011)

Calcium-dependent phosphorylation alters class XIVa myosin function in the protozoan parasite Toxoplasma gondii
por: Tang, Qing, et al.
Publicado: (2014)

TgATAT-Mediated α-Tubulin Acetylation Is Required for Division of the Protozoan Parasite Toxoplasma gondii
por: Varberg, Joseph M., et al.
Publicado: (2016)

Identification of lysine-lactylated substrates in gastric cancer cells
por: Yang, Dawei, et al.
Publicado: (2022)

Global Lysine Crotonylation and 2-Hydroxyisobutyrylation in Phenotypically Different Toxoplasma gondii Parasites
por: Yin, Deqi, et al.
Publicado: (2019)

GLT-1-Dependent Disruption of CNS Glutamate Homeostasis and Neuronal Function by the Protozoan Parasite Toxoplasma gondii
por: David, Clément N., et al.
Publicado: (2016)

The antifungal Aureobasidin A and an analogue are active against the protozoan parasite Toxoplasma gondii but do not inhibit sphingolipid biosynthesis
por: ALQAISI, A. Q. I., et al.
Publicado: (2018)

The protozoan parasite Toxoplasma gondii encodes a gamut of phosphodiesterases during its lytic cycle in human cells
por: Vo, Kim Chi, et al.
Publicado: (2020)

Phagocyte Responses to Protozoan Infection and How Toxoplasma gondii Meets the Challenge
por: Denkers, Eric Y., et al.
Publicado: (2012)

The Motility of a Human Parasite, Toxoplasma gondii, Is Regulated by a Novel Lysine Methyltransferase
por: Heaslip, Aoife T., et al.
Publicado: (2011)

Comprehensive analysis of lysine lactylation in Frankliniella occidentalis
por: An, Dong, et al.
Publicado: (2022)

The Protozoan Parasite Toxoplasma gondii Targets Proteins to Dense Granules and the Vacuolar Space Using Both Conserved and Unusual Mechanisms
por: Karsten, Verena, et al.
Publicado: (1998)

The antifungal Aureobasidin A and an analogue are active against the protozoan parasite Toxoplasma gondii but do not inhibit sphingolipid biosynthesis – Corrigendum
por: ALQAISI, A. Q. I., et al.
Publicado: (2018)

Global Analysis of Lysine Lactylation of Germinated Seeds in Wheat
por: Zhu, Junke, et al.
Publicado: (2023)

Global Proteomic Analysis of Lysine Malonylation in Toxoplasma gondii
por: Nie, Lan-Bi, et al.
Publicado: (2020)

Cellular and Molecular Targets of Nucleotide-Tagged Trithiolato-Bridged Arene Ruthenium Complexes in the Protozoan Parasites Toxoplasma gondii and Trypanosoma brucei
por: Anghel, Nicoleta, et al.
Publicado: (2021)

Cancer therapy in a microbial bottle: Uncorking the novel biology of the protozoan Toxoplasma gondii
por: Fox, Barbara A., et al.
Publicado: (2017)

Systematic Analysis of Lysine Lactylation in the Plant Fungal Pathogen Botrytis cinerea
por: Gao, Mingming, et al.
Publicado: (2020)

Infection by the Protozoan Parasite Toxoplasma gondii Inhibits Host MNK1/2-eIF4E Axis to Promote Its Survival
por: Leroux, Louis-Philippe, et al.
Publicado: (2020)

A state-of-the-art methodology for high-throughput in silico vaccine discovery against protozoan parasites and exemplified with discovered candidates for Toxoplasma gondii
por: Goodswen, Stephen J., et al.
Publicado: (2023)

YiaC and CobB regulate lysine lactylation in Escherichia coli
por: Dong, Hanyang, et al.
Publicado: (2022)

Untargeted Metabolomics Uncovers the Essential Lysine Transporter in Toxoplasma gondii
por: Kloehn, Joachim, et al.
Publicado: (2021)

Proteome-Wide Lysine Acetylation in Cortical Astrocytes and Alterations That Occur during Infection with Brain Parasite Toxoplasma gondii
por: Bouchut, Anne, et al.
Publicado: (2015)

Synthesis vs. salvage of ester- and ether-linked phosphatidylethanolamine in the intracellular protozoan pathogen Toxoplasma gondii
por: Ren, Bingjian, et al.
Publicado: (2023)

A cloth-based hybridization array system for rapid detection of the food- and waterborne protozoan parasites Giardia duodenalis, Cryptosporidium spp. and Toxoplasma gondii
por: Reiling, Sarah J., et al.
Publicado: (2021)

Identification and functional characterization of cis-regulatory elements in the apicomplexan parasite Toxoplasma gondii
por: Mullapudi, Nandita, et al.
Publicado: (2009)

Drug Repurposing Based on Protozoan Proteome: In Vitro Evaluation of In Silico Screened Compounds against Toxoplasma gondii
por: Cajazeiro, Débora Chaves, et al.
Publicado: (2022)

Cellular barcoding of protozoan pathogens reveals the within-host population dynamics of Toxoplasma gondii host colonization
por: Wincott, Ceire J., et al.
Publicado: (2022)

The Neurotropic Parasite Toxoplasma Gondii Increases Dopamine Metabolism
por: Prandovszky, Emese, et al.
Publicado: (2011)

Parasite powerhouse: A review of the Toxoplasma gondii mitochondrion
por: Usey, Madelaine M., et al.
Publicado: (2022)

Lysine lactylation (Kla) might be a novel therapeutic target for breast cancer
por: Deng, Jian, et al.
Publicado: (2023)

Harmonization of Protocols for Multi-Species Organoid Platforms to Study the Intestinal Biology of Toxoplasma gondii and Other Protozoan Infections
por: Holthaus, David, et al.
Publicado: (2021)

Immunity to Protozoan Parasites
por: Lopes, Marcela F., et al.
Publicado: (2012)

Transepithelial Migration of Toxoplasma gondii Is Linked to Parasite Motility and Virulence
por: Barragan, Antonio, et al.
Publicado: (2002)

Secretory traffic in the eukaryotic parasite Toxoplasma gondii : less is more
por: Joiner, Keith A., et al.
Publicado: (2002)

Cannot write session to /tmp/vufind_sessions/sess_i1sjb39ir85ece4fqlf0llq30p