Agomelatine rescues lipopolysaccharide-induced neural injury and depression-like behaviors via suppression of the Gαi-2-PKA-ASK1 signaling pathway

BACKGROUND: Agomelatine has been shown to be effective in the treatment of depression, but the molecular mechanisms underlying its antidepressant effects have yet to be elucidated. Identification of these molecular mechanisms would not only offer new insights into the basis for depression but also p...

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Detalles Bibliográficos
Autores principales: Lan, Tian, Wu, Yuhan, Zhang, Yulei, Li, Shuhan, Zhu, Zhanpeng, Wang, Liyan, Mao, Xueqin, Li, Ye, Fan, Cuiqin, Wang, Wenjing, Yu, Shu Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9131561/
https://www.ncbi.nlm.nih.gov/pubmed/35610704
http://dx.doi.org/10.1186/s12974-022-02479-x

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