LKB1: Can We Target an Hidden Target? Focus on NSCLC

LKB1 (liver kinase B1) is a master regulator of several processes such as metabolism, proliferation, cell polarity and immunity. About one third of non-small cell lung cancers (NSCLCs) present LKB1 alterations, which almost invariably lead to protein loss, resulting in the absence of a potential dru...

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Detalles Bibliográficos
Autores principales: Ndembe, Gloriana, Intini, Ilenia, Perin, Elisa, Marabese, Mirko, Caiola, Elisa, Mendogni, Paolo, Rosso, Lorenzo, Broggini, Massimo, Colombo, Marika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9131655/
https://www.ncbi.nlm.nih.gov/pubmed/35646638
http://dx.doi.org/10.3389/fonc.2022.889826

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9131655/
https://www.ncbi.nlm.nih.gov/pubmed/35646638
http://dx.doi.org/10.3389/fonc.2022.889826

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