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LKB1: Can We Target an Hidden Target? Focus on NSCLC
LKB1 (liver kinase B1) is a master regulator of several processes such as metabolism, proliferation, cell polarity and immunity. About one third of non-small cell lung cancers (NSCLCs) present LKB1 alterations, which almost invariably lead to protein loss, resulting in the absence of a potential dru...
Autores principales: | Ndembe, Gloriana, Intini, Ilenia, Perin, Elisa, Marabese, Mirko, Caiola, Elisa, Mendogni, Paolo, Rosso, Lorenzo, Broggini, Massimo, Colombo, Marika |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9131655/ https://www.ncbi.nlm.nih.gov/pubmed/35646638 http://dx.doi.org/10.3389/fonc.2022.889826 |
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