Structure–antitumor activity relationship of hybrid acetogenins focusing on connecting groups between heterocycles and the linker moiety

We studied hybrid molecules of annonaceous acetogenins and mitochondrial complex I-inhibiting insecticides to develop a novel anticancer agent. A structure–antitumor activity relationship study focusing on the connecting groups between the heterocycles and the linker moiety bearing the tetrahydrofur...

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Detalles Bibliográficos
Autores principales: Ohta, Kaito, Fushimi, Tetsuya, Okamura, Mutsumi, Akatsuka, Akinobu, Dan, Shingo, Iwasaki, Hiroki, Yamashita, Masayuki, Kojima, Naoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9131733/
https://www.ncbi.nlm.nih.gov/pubmed/35685710
http://dx.doi.org/10.1039/d2ra02399g

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9131733/
https://www.ncbi.nlm.nih.gov/pubmed/35685710
http://dx.doi.org/10.1039/d2ra02399g

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