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Structure–antitumor activity relationship of hybrid acetogenins focusing on connecting groups between heterocycles and the linker moiety
We studied hybrid molecules of annonaceous acetogenins and mitochondrial complex I-inhibiting insecticides to develop a novel anticancer agent. A structure–antitumor activity relationship study focusing on the connecting groups between the heterocycles and the linker moiety bearing the tetrahydrofur...
Autores principales: | Ohta, Kaito, Fushimi, Tetsuya, Okamura, Mutsumi, Akatsuka, Akinobu, Dan, Shingo, Iwasaki, Hiroki, Yamashita, Masayuki, Kojima, Naoto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9131733/ https://www.ncbi.nlm.nih.gov/pubmed/35685710 http://dx.doi.org/10.1039/d2ra02399g |
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