CFTR targeted therapies: recent advances in cystic fibrosis and possibilities in other diseases of the airways

Cystic fibrosis transmembrane conductance regulator (CFTR) is an ion transporter that regulates mucus hydration, viscosity and acidity of the airway epithelial surface. Genetic defects in CFTR impair regulation of mucus homeostasis, causing severe defects of mucociliary clearance as seen in cystic f...

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Detalles Bibliográficos
Autores principales: Patel, Sheylan D., Bono, Taylor R., Rowe, Steven M., Solomon, George M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2020
Materias:
Series
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9131734/
https://www.ncbi.nlm.nih.gov/pubmed/32554756
http://dx.doi.org/10.1183/16000617.0068-2019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9131734/
https://www.ncbi.nlm.nih.gov/pubmed/32554756
http://dx.doi.org/10.1183/16000617.0068-2019

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