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Overall Survival in Phase 3 Clinical Trials and the Surveillance, Epidemiology, and End Results Database in Patients With Metastatic Colorectal Cancer, 1986-2016: A Systematic Review

IMPORTANCE: Phase 3 trials for patients with metastatic colorectal cancer (mCRC) have been conducted with varying designs and often with surrogate end points for overall survival (OS). OBJECTIVES: To critically examine the factors associated with clinically relevant improvement in OS (defined as ≥2...

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Detalles Bibliográficos
Autores principales:	Shen, Chan, Tannenbaum, Daniel, Horn, Robert, Rogers, Jane, Eng, Cathy, Zhou, Shouhao, Johnson, Benny, Kopetz, Scott, Morris, Van, Overman, Michael, Parseghian, Christine, Chang, George J., Lopez-Olivo, Maria A., Kanwal, Raghav, Ellis, Lee M., Dasari, Arvind
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Medical Association 2022
Materias:	Original Investigation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9131746/ https://www.ncbi.nlm.nih.gov/pubmed/35608860 http://dx.doi.org/10.1001/jamanetworkopen.2022.13588

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