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Surgery for cervical cancer: consensus & controversies

Surgery plays an important role in the management of early-stage cervical cancer. Type III radical hysterectomy with bilateral pelvic lymph node dissection using open route is the standard surgical procedure. There is level I evidence against the use of laparoscopic/robotic approach for radical hyst...

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Detalles Bibliográficos
Autores principales: Poddar, Pabashi, Maheshwari, Amita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9131770/
https://www.ncbi.nlm.nih.gov/pubmed/34854431
http://dx.doi.org/10.4103/ijmr.IJMR_4240_20
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author Poddar, Pabashi
Maheshwari, Amita
author_facet Poddar, Pabashi
Maheshwari, Amita
author_sort Poddar, Pabashi
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description Surgery plays an important role in the management of early-stage cervical cancer. Type III radical hysterectomy with bilateral pelvic lymph node dissection using open route is the standard surgical procedure. There is level I evidence against the use of laparoscopic/robotic approach for radical hysterectomy for cervical cancer. Emerging data support the use of sentinel lymph node biopsy and nerve sparing radical hysterectomy in carefully selected patients with early-stage disease. In locally advanced cervical cancer patients, the use of neoadjuvant chemotherapy (NACT) followed by radical surgery yields inferior disease-free survival compared to definitive concurrent chemoradiation therapy. Therefore, definitive concurrent chemoradiation is the standard treatment for locally advanced disease. Fertility preserving surgery is feasible in highly selected young patients. Role of less-radical surgical procedures in patients’ with low-stage disease with good prognostic factors is under evaluation.
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spelling pubmed-91317702022-05-26 Surgery for cervical cancer: consensus & controversies Poddar, Pabashi Maheshwari, Amita Indian J Med Res Review Article Surgery plays an important role in the management of early-stage cervical cancer. Type III radical hysterectomy with bilateral pelvic lymph node dissection using open route is the standard surgical procedure. There is level I evidence against the use of laparoscopic/robotic approach for radical hysterectomy for cervical cancer. Emerging data support the use of sentinel lymph node biopsy and nerve sparing radical hysterectomy in carefully selected patients with early-stage disease. In locally advanced cervical cancer patients, the use of neoadjuvant chemotherapy (NACT) followed by radical surgery yields inferior disease-free survival compared to definitive concurrent chemoradiation therapy. Therefore, definitive concurrent chemoradiation is the standard treatment for locally advanced disease. Fertility preserving surgery is feasible in highly selected young patients. Role of less-radical surgical procedures in patients’ with low-stage disease with good prognostic factors is under evaluation. Wolters Kluwer - Medknow 2021-08 /pmc/articles/PMC9131770/ /pubmed/34854431 http://dx.doi.org/10.4103/ijmr.IJMR_4240_20 Text en Copyright: © 2022 Indian Journal of Medical Research https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Review Article
Poddar, Pabashi
Maheshwari, Amita
Surgery for cervical cancer: consensus & controversies
title Surgery for cervical cancer: consensus & controversies
title_full Surgery for cervical cancer: consensus & controversies
title_fullStr Surgery for cervical cancer: consensus & controversies
title_full_unstemmed Surgery for cervical cancer: consensus & controversies
title_short Surgery for cervical cancer: consensus & controversies
title_sort surgery for cervical cancer: consensus & controversies
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9131770/
https://www.ncbi.nlm.nih.gov/pubmed/34854431
http://dx.doi.org/10.4103/ijmr.IJMR_4240_20
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