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A randomized, double-blind, parallel-group, single-dose comparative pharmacokinetic study of DRL_TZ, a candidate biosimilar of trastuzumab, with Herceptin(®) (EU) in healthy adult males

BACKGROUND & OBJECTIVES: Trastuzumab (TZ) is a recombinant DNA-derived humanized monoclonal antibody approved for human epidermal growth factor receptor 2 positive early breast cancer, metastatic breast and gastric cancers. For the development of TZ biosimilars, establishing pharmacokinetic equi...

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Detalles Bibliográficos
Autores principales:	Lickliter, Jason D., Dadhania, Rakesh Naranbhai, Trivedi, Ravi Kumar, Kumar, S.R. Naveen, Reddy, Pramod Kumar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Wolters Kluwer - Medknow 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9131799/ https://www.ncbi.nlm.nih.gov/pubmed/35142643 http://dx.doi.org/10.4103/ijmr.IJMR_1119_18

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